Colloid degeneration of the skin, or the so-called colloid milium, was first described by Wagner in 1866. Since that time, about twenty well authenticated cases have been reported. It is a rare dermatosis of unknown etiology, characterized by a hyaline-like degeneration of the collagen bundles of the cutis. The lesions almost invariably occur on the exposed surfaces, and are either discrete or confluent yellowish nodules, from which can be expressed a thick, glary material. Because of the rarity of the disease, and as it embodies several unusual features, it was thought advisable to add a detailed report of this case to the existing literature. REPORT OF CASE History.— A housewife, aged 47, a Russian Jewess, presented herself at the Dermatologic Service of the University Hospital, complaining of an eruption on the forehead. Because of language difficulty, only a meager history was obtained. The family history was essentially negative, except that