Distribution of HLA Antigens in Patients with Ewing's Sarcoma

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Abstract
Thirty-eight unrelated Caucasian patients with Ewing''s sarcoma were typed for HLA-A and B locus antigens. Although no significant differences in the distribution of these antigens were found in comparison with local controls, a trend towards increases in HLA-B8 and Aw19 complex antigens was noted. Although American blacks are only rarely affected by this tumor, the 2 black patients typed both had the HLA-Aw19 complex antigen, Aw31. A disease susceptibility factor may be in linkage disequilibrium with HLA-Aw19 complex HLA antigens.

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