Induction of human γ interferon by Sarcophaga peregrina humoral lectin
- 1 October 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 175 (2) , 325-328
- https://doi.org/10.1016/0014-5793(84)80761-9
Abstract
Humoral lectin isolated from the hemolymph of injured Sarcophaga peregrina(flesh‐fly) larvae was found to activate human peripheral blood cells to produce interferon activity. This interferon was inactivated by dialysis against a solution of pH 2.0 and by heat treatment at 56°C for 30 min, indicating that it was a γ interferon. The role of this lectin in the defence mechanism is discussed from the viewpoint of comparative immunology.Keywords
This publication has 6 references indexed in Scilit:
- Measurement of Sarcophaga peregrina lectin under various physiological conditions by radioimmunoassay.Journal of Biological Chemistry, 1983
- Induction of human leukocyte interferon by heat-treated poly I: Poly CBiochemical and Biophysical Research Communications, 1983
- Purification of lectin induced in the hemolymph of Sarcophaga peregrina larvae on injury.Journal of Biological Chemistry, 1980
- A rapid method for the isolation of functional thymus‐derived murine lymphocytesEuropean Journal of Immunology, 1973
- Tissue Typing Using a Routine One‐Step Lymphocyte Separation ProcedureBritish Journal of Haematology, 1970
- AN INHIBITOR OF VIRAL ACTIVITY APPEARING IN INFECTED CELL CULTURESProceedings of the National Academy of Sciences, 1959