Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11
- 1 August 1985
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 70 (4) , 337-340
- https://doi.org/10.1007/bf00295373
Abstract
A 0.9 kb cDNA fragment, corresponding to a large part of Rhesus monkey pepsinogen A mRNA, was used as probe for the chromosomal localization of the human pepsinogen A gene(s) using human-rodent somatic cell hybrids. Southern blot analysis of 14 human-Chinese hamster and three human-mouse cell hybrids, strongly indicates that the human PGA locus is on chromosome 11. The human-mouse hybrids, containing a translocation involving chromosome 11, allow sublocalization to the region q12-pter.Keywords
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