Effect of stereotaxic surgery upon electroencephalographic status of parkinsonian patients

Publisher Website
Google Scholar
Abstract
Electroencephalograms were taken on 223 Parkinsonian patients. Preoperatively, 64% of the records were normal; 36% reflected electroencephalographic abnormalities. One hundred eighteen of these patients had a single therapeutic operative procedure with one or more radiofrequency lesions placed in the ventrolateral thalamus or globus pallidus, or both, and an electroencephalographic record taken within the 1-through 8-month postoperative period. Patients having normal electroencephalograms preoperatively had about a 50-50 chance of retaining a normal electroencephalogram alter surgery. Surgery had the effect of normalizing a small percentage of records that had been abnormal preoperatively. The most prominent electro-cephalographic abnormality resulting from therapeutic lesions was the occurrence of diffuse or focal slowing, or both, in both the theta and delta frequencies; additional bursts of slow waves and random spikes or sharp waves occurred less frequently. Postoperative foci were seen most often in the temporal region but also appeared in central, frontal, and parietal?regions. These foci were predominantly ipsilateral to the side of lesion, with a very low incidence of bilateral focal activity. Amplitue asymmetry was sometimes observed, with increased voltage occurring on the operated side. The size of the opening into the skull, whether burr hole or trephine, did not seem to affect the probability of encountering an abnormal postoperative record. There did not appear to be any relationship between target site (globus pallidus versus lateral ventral thalamus) or side (right versus left) and electronencephalographic abnormality.

This publication has 0 references indexed in Scilit: