Abstract
Summary: : An analysis of all early onset neonatal Group B streptococcal (GBS) infections at the Royal Women's Hospital, Melbourne was made for the 10-year period 1979–1988. There were 104 cases with 29 neonatal deaths (28%). One or more predisposing perinatal risk factors was evident in 82% of cases (premature labour 79%, prolonged membrane rupture (> 12 hours) 57%, premature rupture of the membranes 69%, maternal sepsis 29%). Overall, 88% of GBS infections were evident within 24 hours of birth, suggesting an intrapartum pathogenesis for infection.