Pattern of acetate incorporation into the aglycone of chartreusin. Evidence from 13C nuclear magnetic resonance studies for a single-chain polyketide intermediate

1 January 1976

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 9,p. 319-320
https://doi.org/10.1039/c39760000319

Abstract

¹³ C N.m.r. analysis of the labelling pattern in chartreusin biosynthesized from singly and doubly ¹³C- labelled acetate has indicated that the aglycone is formed by condensation and subsequent scission of a single polyketide chain of 22 carbon atoms.