HYPOPROTHROMBINEMIA FOLLOWING THE USE OF PROPYLTHIOURACIL: CASE REPORT

1 November 1955

journal article
research article
Published by American College of Physicians in Annals of Internal Medicine

Vol. 43 (5) , 1124-1127
https://doi.org/10.7326/0003-4819-43-5-1124

Abstract

A 43-year-old white Italian female who was treated with propylthiouracil for 6 months because of hyperthyroidism developed bleeding from the genitourinary tract, and purpura, with hypoprothrombinemia and a prolonged clotting time. There was a dramatic salutary response to blood transfusions, vitamin K1 oxide and coritsone.

Keywords

PROPYLTHIOURACIL
HYPOPROTHROMBINEMIAS