Pulmonary function abnormalities and airway irritation symptoms of metal fumes exposure on automobile spot welders
- 11 May 2006
- journal article
- research article
- Published by Wiley in American Journal of Industrial Medicine
- Vol. 49 (6) , 407-416
- https://doi.org/10.1002/ajim.20320
Abstract
Background Spot or resistance welding has been considered less hazardous than other types of welding. Automobile manufacturing is a major industry in Taiwan. Spot and arc welding are common processes in this industry. The respiratory effects on automobile spot welders exposed to metal fumes are investigated. Methods The cohort consisted of 41 male auto‐body spot welders, 76 male arc welders, 71 male office workers, and 59 assemblers without welding exposure. Inductivity Coupled Plasma Mass Spectrophotometer (ICP‐MS) was applied to detect metals' (zinc, copper, nickel) levels in the post‐shift urine samples. Demographic data, work history, smoking status, and respiratory tract irritation symptoms were gathered by a standard self‐administered questionnaire. Pulmonary function tests were also performed. Results There were significantly higher values for average urine metals' (zinc, copper, nickel) levels in spot welders and arc welders than in the non‐welding controls. There were 4 out of 23 (17.4%) abnormal forced vital capacity (FVC) among the high‐exposed spot welders, 2 out of 18 (11.1%) among the low‐exposed spot welders, and 6 out of 130 (4.6%) non‐welding‐exposed workers. There was a significant linear trend between spot welding exposure and the prevalence of restrictive airway abnormalities (P = 0.036) after adjusting for other factors. There were 9 out of 23 (39.1%) abnormal peak expiratory flow rate (PEFR) among high‐exposed spot welders, 5 out of 18 (27.8%) among the low‐exposed spot welders, and 28 out of 130 (21.5%) non‐welding‐exposed workers. There was a borderline significant linear trend between spot welding exposure and the prevalence of obstructive lung function abnormalities (P = 0.084) after adjusting for other factors. There was also a significant dose‐response relationship of airway irritation symptoms (cough, phlegm, chronic bronchitis) among the spot welders. Arc welders with high exposure status also had a significant risk of obstructive lung abnormalities (PEFR reduction). There was also a significant dose‐response relationship of airway irritation symptoms (cough, phlegm, chest tightness, and chronic bronchitis) among the arc welders. Conclusions These findings suggest that restrictive and obstructive lung abnormalities, and airway irritation symptoms are associated with spot and arc welding exposures. Am. J. Ind. Med. 49:407–416, 2006.Keywords
This publication has 23 references indexed in Scilit:
- Interstitial pulmonary fibrosis after severe exposure to welding fumesAmerican Journal of Industrial Medicine, 2002
- Airway Reactivity in WeldersJournal of Occupational and Environmental Medicine, 1996
- Ocular Hazards of Industrial Spot WeldingOptometry and Vision Science, 1996
- Respiratory health of young shipyard welders and other tradesmen studied cross sectionally and longitudinally.Occupational and Environmental Medicine, 1995
- Transient changes in the pulmonary function of welders: a cross sectional study of Monday peak expiratory flow.Occupational and Environmental Medicine, 1994
- The Respiratory Health of WeldersAmerican Review of Respiratory Disease, 1991
- Ozone-induced Inflammation in the Lower Airways of Human SubjectsAmerican Review of Respiratory Disease, 1989
- Transformation of alveolar Type 2 cells to Type 1 cells following exposure to NO2Experimental and Molecular Pathology, 1975
- Cell Renewal in the Lungs of Rats Exposed to Low Levels of NO2Archives of environmental health, 1972
- Covert Pathogenesis of NO2Induced Emphysema in the RatArchives of environmental health, 1965