Absence of significant autosomal lesions in Huntington's disease
- 1 October 1985
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 49 (4) , 283-290
- https://doi.org/10.1111/j.1469-1809.1985.tb01704.x
Abstract
Summary: Peripheral blood from six patients with Huntington's disease (HD) and six controls were cultured in three types of media known to produce fragile sites. A total of 3000 metaphases per group were scrutinized in a blind coded study. No significantly specific ‘hot‐spot’ was found capable of differentiating between HD patients and controls.Keywords
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