Labial Pits--Cleft Lip and/or Palate Syndrome: A Report of Five New Families

1 May 1970

journal article
research article
Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery

Vol. 91 (5) , 407-411
https://doi.org/10.1001/archotol.1970.00770040601002

Abstract

Genealogical and clinical findings of five new families with the syndrome of pits of the lower lips and clefts of lip and palate (PiCLCP) suggest that the condition is transmitted as an autosomal dominant trait with—in most instances—complete penetrance of the mutant gene. The phenotype manifestations vary considerably from case to case. A satisfactory cosmetic result can be achieved by total excision of the pits provided one preserves the vermilion border.

Keywords

This publication has 4 references indexed in Scilit:

Cleft lip, cleft palate, and congenital fistulas of the lower lip
Oral Surgery, Oral Medicine, Oral Pathology, 1967
Congenital fistulas of the lower lip
Oral Surgery, Oral Medicine, Oral Pathology, 1966
Congenital sinuses of the lower lip
Oral Surgery, Oral Medicine, Oral Pathology, 1961
Remarks on the Etiology of Congenital Bilateral Fistulae of the Lower Lip
Plastic and Reconstructive Surgery, 1952