Tautomeric rearrangement of 3-deoxy-3-thioureidoaldoses: a novel synthetic route to carbohydrate mimics having a cyclic thiourea structure
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 17,p. 2077-2078
- https://doi.org/10.1039/cc9960002077
Abstract
Cyclic thiourea glycomimetics structualy related to 3-deoxyy-2-nonulosonic acid (KDNs) and 1,5-dideoxy-1,5-iminooctitols (azaoctitols) have been prepared by tautomeric rearrangement of 3-decoy-3-thioureidoaldohexoses; the conformational properties of these compounds are governed by stereoelectronic requirements, mainly the anomeric effect.Keywords
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