Does carbamazepine-induced reduction of plasma haloperidol levels worsen psychotic symptoms?
- 1 May 1986
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 143 (5) , 650-651
- https://doi.org/10.1176/ajp.143.5.650
Abstract
Seven psychotic patients'' plasma haloperidol levels, determined with gas-liquid chromatography, fell a mean of 60% when carbamazepine treatment was instituted. Two patients'' levels became undetectable, and their symptoms worsened. Haloperidol level monitoring may be required for patients given both haloperidol and carbamazepine.This publication has 1 reference indexed in Scilit:
- Relationship of serum haloperidol levels to clinical response in schizophrenic patientsAmerican Journal of Psychiatry, 1981