NK cells and apoptosis
- 1 February 1999
- journal article
- review article
- Published by Wiley in Immunology & Cell Biology
- Vol. 77 (1) , 64-75
- https://doi.org/10.1046/j.1440-1711.1999.00790.x
Abstract
Natural killer (NK) cells are a cell of the innate immune system that play an important role in the early response to viral infections and tumours. Natural killer cells are cytolytic, and secrete cytokines that influence the developing antigen-specific immune response. In the present article the NK cell surface molecules regulating effector function, the NK cell effector mechanisms involved in apoptosis, and the role of NK cell effector mechanisms in immune responses are reviewed.Keywords
Funding Information
- Wellcome Trust
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