ESTIMATIONS OF THE RAPIDITY AND AMOUNT OF BLOOD TRAVERSING THE SHORTER PATHS OF THE SYSTEMIC CIRCULATION

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Abstract
An experimental arrangement- for these determinations in anesthetized dogs is described. The average results show that over 35% of the blood put out by the left heart returned to the right heart within 15 sec. The percentage rapidly returning bore a direct relationship to the height of the mean blood pressure. No relationship to the cardiac output was demonstrated. A mechanism is suggested capable of producing changes in the gas content of mixed venous blood in times shorter than that required for blood to traverse the shortest systemic circuits. The relationship of these findings to problems involved in the estimation of cardiac output in man is discussed.

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