Pro-atrial natriuretic peptide hormone from right atria is correlated with cardiac depression in septic patients
- 1 July 2001
- journal article
- Published by Springer Nature in Journal of Endocrinological Investigation
- Vol. 24 (7) , RC22-RC24
- https://doi.org/10.1007/bf03343878
Abstract
N-terminal pro-atrial natriuretic peptide [proANP(1–98)] has been extensively investiga-ted in patients with chronic heart failure and ishemic heart disease. It is found to be a better marker of cardiac dysfunction than atrial natriuretic peptide (ANP). The possible involvement of proANP(1–98) in cardiac depression caused by sepsis has not been studied yet. Therefore, we analyzed atrial plasma concentration of proANP(1–98) in 17 septic patients with hemodynamic variables measured or calculated using pulmonary artery catheter. The results of altogether 96 measurements show a significant negative correlation of proANP(1–98) and cardiac index (pARDS) (pARDS.Keywords
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