Synthesis ofL-quisqualic acid: a general method for enantio-efficient synthesis of β-aminoalanine derivatives
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 5,p. 256-257
- https://doi.org/10.1039/c39850000256
Abstract
A general method for the enantio-efficient synthesis of β-aminoalanine derivatives, which involves intramolecular transfer of the amino substituent from the αcarboxy to the β-carbon atom via an azetidinone is described with its application to an efficient synthesis of the neuroexcitatory quisqualic acid in an optically pure state.Keywords
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