Comparison of colophony patch test preparations

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Abstract
The patch test reactivity to different petrolatum preparations and concentrations of colophony (gum rosin) was compared. A serial dilution lest with gum rosin 20%‐0.001% gave a clear dose‐response relationship with a maximum response 10% and 20%. Patch testing with 60% in the routine lest did not reveal any further cases compared to simultaneous testing with 20%. Irritancy to the 60% concentration was seen in some cases. A good correlation in reactivity was found between commercially‐supplied lest preparations for routine testing and homogeneous preparations made up in our laboratory. Our results imply that a concentration of 10% is well worth considering fur routine testing.