Influence of the 2’-Chloro Substitution on Central Activity of Desmethyldiazepam

1 January 1978

journal article
research article
Published by S. Karger AG in Pharmacology

Vol. 17 (3) , 121-127
https://doi.org/10.1159/000136845

Abstract

Two diazepam derivatives, the N-desmethyl and the 2’-chlor-N-desmethyldiazepam, were compared in rats using behavioral and EEG techniques. Both drugs had depressant effects upon locomotor activity, fa

Keywords

2’-CHLOR-N-DESMETHYLDIAZEPAM
CONFLICT BEHAVIOR
EEG
LOCOMOTOR ACTIVITY
N-DESMETHYLDIAZEPAM
SIDMAN AVOIDANCE

This publication has 3 references indexed in Scilit:

On the hypnogenic and anticonvulsant activities of demethyldiazepam and chlordemethyldiazepam: time-effect relations
Journal of Pharmacy and Pharmacology, 1977
EFFECTS OF CHLORDESMETHYLDIAZEPAM ON BEHAVIORAL PERFORMANCE AND SUBJECTIVE JUDGMENT IN NORMAL SUBJECTS
1976
Effect of desmethyldiazepam and chlordesmethyldiazepam on 3?,5?-cyclic guanosine monophosphate levels in rat cerebellum
Psychopharmacology, 1976