Link between Epilepsy and Malnutrition in a Rural Area of Benin

Abstract
Summary: Purpose: Epilepsy and malnutrition are both important public health problems in sub‐Saharan Africa. A relationship between epilepsy and malnutrition has been suspected for many years. Our objective was to investigate the association between epilepsy and malnutrition in Djidja, Benin. Methods: A matched population‐based cross‐sectional case–control survey was performed: cases (patients with epilepsy) were matched to controls according to sex, age ± 5 years, and village of residence. The World Health Organization's criteria for malnutrition was used. Anthropometric measurements (weight, height, mid arm upper circumference, triceps skinfold thickness) were taken. Bioelectrical impedance analysis, a standardized food and social questionnaire and a clinical examination were done. Statistical analysis (conditional logistic regression) was performed using SAS 8.0. Results: A total of 131 cases and 262 controls were included. The prevalence of malnutrition was higher in cases than in controls (22.1% vs. 9.2%, p = 0.0006). Social factors were significantly different between cases and controls. Feeding difficulties were more frequent and health status was worse in cases. Seven variables were associated with epilepsy: (i) nutritional factors: mid arm upper circumference (prevalence odds ratio (pOR) = 0.7, CI: 0.6–0.9), cereal consumption Conclusion: Epilepsy and nutritional status are linked in sub‐Saharan Africa. Programs to improve the nutritional status of people with epilepsy are needed.