EFFECT OF SLOPE OF ALVEOLAR PLATEAU ON DETERMINATION OF CLOSING VOLUME

  • 1 January 1978
    • journal article
    • research article
    • Vol. 59  (2) , 82-90
Abstract
Repeated closing volume (CV) determinations were obtained simultaneously with the N method (CV-N2) and with a He bolus method (CV-He) in 19 selected subjects with normal routine spirometry. Subjects (10) had normal slopes of phase III and 9 had abnormally steep slopes of phase III obtained with the N method. No systematic difference was found between CV-N2 and CV-He irrespective of the steepness of phase III, which seems to indicate that at least in spirometrically normal subjects airway closure is adequately assessed by the N method even in the presence of a steep slope of phase III.