Isoprenaline-induced myocardial infarction in spontaneously hypertensive rats
- 1 August 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 13 (8) , 450-458
- https://doi.org/10.1093/cvr/13.8.450
Abstract
Spontaneously hypertensive rats were subjected to massive myocardial infarction. The pathophysiological changes were similar to those of normotensive rats but the spontaneously hypertensive rats developed congestive heart failure during myocardial repair rather than during the necrosis phase and survived in superior numbers. Blood pressure fell despite maximally increased corticosterone levels. Atrial and ventricular thromboses and left ventricular aneurysm formation were frequent.Keywords
This publication has 1 reference indexed in Scilit:
- Arterial lesions in repeatedly bred spontaneously hypertensive rats.Circulation Research, 1976