Abstract
HIV disease can have significant implications for the psychological status of the individual, and one important aspect is that of self-destructive behavior. The range of suicidal behaviors found at the different stages of HIV disease are considered, with a review of the research evidence about HIV asymptomatics, AIDS, and end-stage disease. A critical discussion of methodological issues in HIV-related suicidal behavior examines the importance of study design, sample selection, operational criteria and illness staging. The possible mechanisms of suicide risk and clinical management issues are discussed. Finally, critical questions relevant to further research are highlighted.