Follow‐up Study of Survivors after Intra‐uterine Transfusion

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Abstract
Between 1965-1976 217 infants received intra-uterine transfusions. Perinatal and follow-up data were presented on the 81 survivors, of whom 62% were over 5 yr of age at final follow-up. Assessment included development and general health, audiometric testing and school performance. Abnormalities were found in 29 of the survivors. In 13 cases these were attributed to hemolytic disease, and all had some neurological deficit such as differing degrees of deafness. Ten others had slight abnormalities associated with the procedure of intra-uterine transfusion, while 6 had abnormalities not associated with either (spastic quadriplegia following infection, congenital heart disease and visual disorders). The remaining 52 children were normal. Hyperbilirubinemia is probably responsible for the neurological deficits.

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