SOME CIRCULATORY AND RESPIRATORY EFFECTS OF MORPHINE IN PATIENTS WITHOUT PRE-EXISTING CARDIAC DISEASE
Open Access
- 1 September 1977
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 49 (9) , 927-933
- https://doi.org/10.1093/bja/49.9.927
Abstract
Haemodynamic and respiratory effects of i.v. morphine (10 mg/70 kg body weight) were studied in 10 adults with unimpaired circulatory function. There were significant changes in mean arterial pressure, mean heart rate, respiratory rate and tidal volume, at 10-, 30- and 60-min intervals. Transient changes in mean total systemic resistance and mean stroke volume were also seen at 10 min. The results strongly suggest a peripheral vasodilator response to morphine. Respiratory depression was not demonstrated.This publication has 4 references indexed in Scilit:
- Effects of Premedicant Drugs on Respiration and Gas Exchange in ManAnesthesiology, 1967
- ELEVATION OF PLASMA HISTAMINE LEVELS IN DOG FOLLOWING ADMINISTRATION OF MUSCLE RELAXANTS OPIATES + MACROMOLECULAR POLYMERS1964
- Role of the Nervous System in the Control of Vascular ToneCirculation, 1960
- STUDIES ON THE CIRCULATIONAmerican Journal of Physiology-Legacy Content, 1929