Ocular and systemic abnormalities associated with morning glory syndrome

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Abstract
The term: ‘morning glory syndrome’ is currently used to describe a clinical complex encompassing a primarily congenital, possibly hereditary optic nerve anomaly associated with other ocular and systemic abnormalities. This syndrome has been shown to be usually limited to the eye with non-involvement of the retrobulbar nerve and brain. However, recent studies have illustrated that morning glory syndrome may be associated with such systemic abnormalities as sphenoidal encephalocele. The authors present a review of the current literature and functionally analyze the incidence of retinal detachment, pre-retinal gliosis, increased production of fibrovascular tissue and other ocular abnormalities; as well as exploring the association of systemic involvement; utilizing fluorescein angiography, computerized tomography, ultrasonography and electrophysiology.

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