Light and electron microscopy of intestinal ferritin absorption. Observations in sensitized and nonsensitized hamsters (Mesocricetus auratus)

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Abstract
The intestinal absorptive cells of adult hamsters which have been pretreated with intraperitoneal injections of horse ferritin or subcutaneous injections of ferritin‐adjuvant mixture show a marked absorption of this protein when it is introduced into ligated segments of the intestinal lumen for periods up to three hours.Ferritin is concentrated in the enteric surface coating, intracytoplasmic vesicles in the supranuclear area, and the Golgi apparatus. Large aggregates are localized in macrophages, fibrocytes, and endothelial cells of the lamina propria. Individual molecules are also present in these cells, plasma cells, intercellular spaces and capillary lumens.