Amniography in prenatal diagnosis.

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Abstract
The increasing use of [human] prenatal diagnostic methods, including sonography and amniotic fluid analysis made it possible to suspect certain fetal defects at a nearly gestational age. In selected cases accurate diagnosis of the specific malformation may have an effect on fetal and neonatal prognosis and on prenatal counseling of the parents. As part of a large regional screening program for neural tube defects, 28 midtrimester amniograms were performed. Fourteen neural tube defects (9 spina bifida, 4 anencephaly, 1 Meckel syndrome), 4 abdominal wall defects, 2 tumors and 8 normal examinations were found. Radiographic examples of these malformations are presented, including previously undescribed findings in meningomyeloceles. The place of amniography in prenatal diagnosis is discussed.

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