Melanocyte mitosis in UVB-irradiated mouse skin
Open Access
- 1 May 1978
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Dermato-Venereologica
- Vol. 58 (3) , 217-221
- https://doi.org/10.2340/0001555558217221
Abstract
Little is known about the mitotic activity of the epidermal melanocyte population. Vincristine sulphate has now been used in vivo to study the frequency of mitosis of epedermal melanocytes in the ear skin of C57BL mice. It is shown that there is continuous formation of new melanocytes in unstimulated skin due to mitosis of pigment-producing epidermal melanocytes. The increase in this mitotic rate following daily UVB irradiation suggests that this is a major mechanism responsible for the UV-induced increase in the epidermal melanocyte population.This publication has 6 references indexed in Scilit:
- Thymidine labelling of epidermal melanocytes in UV-irradiated skinActa Dermato-Venereologica, 1975
- Cell proliferation in stratified squamous epithelium in miceExperimental Cell Research, 1968
- Melanocyte Populations in UV-irradiated Human Skin**From the Division of Biological and Medical Sciences, Brown University, Providence, R.I., the Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Mass. and the Rhode Island Medical Center, Howard, R.I.Journal of Investigative Dermatology, 1965
- TRITIATED THYMIDINE VERSUS COLCHICINE TECHNIQUE IN STUDY OF CELL POPULATION CYTODYNAMICS1964
- MELANOCYTES AND MELANIN IN HUMAN ABDOMINAL WALL SKIN - A SURVEY MADE AT DIFFERENT AGES IN BOTH SEXES AND DURING PREGNANCY1963
- A STUDY OF EFFECT OF CHRONIC IRRITATION ON MELANOGENESIS IN SKIN1962