Integrating natural product synthesis and combinatorial chemistry
- 1 July 2001
- journal article
- Published by Walter de Gruyter GmbH in Pure and Applied Chemistry
- Vol. 73 (7) , 1033-1039
- https://doi.org/10.1351/pac200173071033
Abstract
The fields of natural product total synthesis and combinatorial chemistry have major differences as well as much in common. Unique to combinatorial chemistry is the need to devise rapid and efficient methods for parallel synthesis and purification, while an area of overlap is the targeting of natural product scaffolds for combinatorial libraries. Both these aspects are illustrated with examples from our research.Keywords
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