Efficient, Racemization-Free Amidation of Protected Amino Acids
- 1 January 1992
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1992 (03) , 285-287
- https://doi.org/10.1055/s-1992-26093
Abstract
N-tert-Butoxycarbonyl derivatives of L-leucine, S-benzyl-L-cysteine and Nt-(2,4-dinitrophenyl)-L-histidine were amidated with crystalline ammonium, methylammonium, and ethylammonium salts of 3-hydroxy-1,2,3-benzotriazin-4(3H)-one and N-hydroxysuccinimide to give the corresponding amino acid amides in good yield and with good optical purity.Keywords
This publication has 0 references indexed in Scilit: