The Practical Synthsis of N-Protected Allylamine: The Isoxazoline Route to Statine Analogue

1 January 1989

journal article
research article
Published by CLOCKSS Archive in HETEROCYCLES

Vol. 29 (9) , 1835-1842
https://doi.org/10.3987/com-89-5076

Abstract

The facile, practical synthesis of optically active N-protected allylamine from .alpha.-amino acid is described. The evolution of this work in the synthesis of statine analogue using [3+2] cycloaddition reaction is detailed.

Keywords

HETEROCYCLES

This publication has 1 reference indexed in Scilit:

Diastereofacial selection in nitrile oxide cycloaddition reactions. The anti-directing effect of an allylic oxygen and some new results on the ring metalation of isoxazolines. A synthesis of (.+-.)-blastmycinone
The Journal of Organic Chemistry, 1984