Phosphoglycollohydroxamic acid: an inhibitor of class I and II aldolases and triosephosphate isomerase. A potential antibacterial and antifungal agent
- 1 January 1973
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 19,p. 713-715
- https://doi.org/10.1039/c39730000713
Abstract
The exceptionally strong binding of phosphoglycollohydroxamic acid to the metallo-aldolase from Bacillus stearothermophilus(Kica. 2 × 10–9 M) compared with rabbit muscle aldolase (Kica. 2 × 10–6 M) and chicken triosephosphate isomerase (Kica. 14 × 10–6 M) suggests that it may be a useful antibacterial and antifungal agent.Keywords
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