A CHROMOSOME SURVEY IN 40 SEXUALLY ABNORMAL PATIENTS

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Abstract
The study on chromosome number was carried out with cultured leucocytes from blood of patients in 6 cases of Klinefelter''s syndrome, 1 of Turner''s syndrome, 10 of cryptorchism, 8 of azoospermia, 3 each of hypo-spadias and eunuchoidism, 2 each of female pseudohermaphroitism and gynecomastia, and 1 each of adrenogenital syndrome, gyneatresia totalis congenitalis, ectopic testis and epispadia. The XXY sex-chromosome constitution was detected in the 6 Klinefelter''s syndrome cases and the XO mechanism in the Turner''s syndrome patient. Each of the 33 cases with clinical sex anomalies were found to possess an apparently normal chromosome complement in terms of number and morphology.