THE EFFECT OF GROWTH HORMONE ON LIPOGENESIS IN INTACT AND ADRENALECTOMIZED RATS
- 1 May 1955
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 56 (5) , 579-583
- https://doi.org/10.1210/endo-56-5-579
Abstract
Incorporation of acetate 2-C14 into fatty acids by liver slices from intact and adrenalectomized rats was observed and the effect of growth hormone on this process studied. Growth hormone was found to inhibit lipogenesis in both intact and adrenalectomized animals. In the latter it further depressed the low acetate incorporation already present in comparison to intact controls. It was concluded that the presence of adrenal cortical hormones was not necessary for growth hormone to affect the process of fat formation.Keywords
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