Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis
- 4 May 1999
- journal article
- Published by Elsevier in Neuroscience
- Vol. 91 (3) , 819-830
- https://doi.org/10.1016/s0306-4522(98)00599-5
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor proteinNature, 1998
- Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In VivoNeuron, 1996
- Synaptic pathology in Alzheimer's disease: Relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 alleleJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1996
- Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's diseaseJournal of Neuroscience, 1996
- Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19 [published erratum appears in Endocrinology 1995 Feb;136(2):795]Endocrinology, 1994
- Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.The Journal of cell biology, 1993
- Microwave Modification of Bielschowsky Silver Impregnation Method for Diagnosis of Alzheimer's DiseaseJournal of Histotechnology, 1992
- The amyloid β protein precursor or proteinase nexin II from mouse is closer related to its human homolog than previously reportedBiochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1991
- Rapid, Reliable and Economical Silver Stain for Neurofibrillary Tangles and Senile PlaquesJournal of Histotechnology, 1991
- A Heparin Binding Protein Whose Expression Increases during Differentiation of Embryonal Carcinoma Cells to Parietal Endoderm Cells: cDNA Cloning and Sequence Analysis1The Journal of Biochemistry, 1990