Antigenic Characteristics of Three Variants of Rous Sarcoma Virus
Open Access
- 1 November 1963
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 31 (5) , 1275-1283
- https://doi.org/10.1093/jnci/31.5.1275
Abstract
Three antigenic variants of Rous sarcoma virus are described by use of a neutralization test. Strain RSV(H) showed little or no cross-neutralization when tested against the other strains. There was partial cross-neutralization between the remaining two variants, RSV(B) and RSV(29). Antiserum prepared in turkeys was less specific than chicken antiserum, i.e., turkey antisera cross-neutralized more frequently and showed higher levels of cross-reaction. Chicken serum having “naturally occurring” antibodies neutralized RSV(B) but not RSV(H). Rous antibody-free chicken serum failed to neutralize either of the major antigenic types.Keywords
This publication has 5 references indexed in Scilit:
- Biological Properties of Three Variants of Rous Sarcoma VirusJNCI Journal of the National Cancer Institute, 1963
- THE PATTERN OF CONGENITAL TRANSMISSION OF AN AVIAN LEUKOSIS VIRUSProceedings of the National Academy of Sciences, 1961
- Quantitative studies on Rous sarcoma virusVirology, 1960
- Quantitative studies of the relationships between infecting dose of Rous sarcoma virus, antiviral immune response, and tumor growth in chickensVirology, 1960
- Biological Studies on the Rous Sarcoma Virus. V. Preparation of Improved Standard Lots of the Virus for Use in Quantitative InvestigationsJNCI Journal of the National Cancer Institute, 1956