Hyperlipoproteinemias in the etiology of inner ear disease

Abstract
This paper is the report of a study of 300 patients with symptoms or findings indicative of the presence of inner ear disease who were studied and tested by lipoprotein phenotyping, and an incidence of 42.33 percent was found to have clearly defined hyperlipoproteinemia (HLP) on the basis of the laboratory tests with an additional 8.66 percent whose tests were presumptive enough to permit their classification as being hyperlipoproteinemic. Hyperlipoproteinemia has its greatest clinical significance in that its correlation with coronary artery disease (CAD) makes its early detection and subsequent treatment, at least by dietary control, most important in preventing the excessive mortality from atherosclerosis and its complications. The statistically high incidence of HLP in the 300 patients reported in this paper, who had either or both cochlear and vestibular symptoms, adds further credence to the work, observations, and reports of Rosen, whose epidemiological studies show a high correlation of hearing loss with elevated cholesterol, atherosclerosis, and coronary artery disease in those population groups whose dietary intake of saturated fats is high.Otologists now need to join hands with the internists and pediatricians in seeking an early diagnosis of hyperlipoproteinemia. In so doing, a metabolic abnormality which apparently leads to labyrinthine dysfunction, coronary artery disease, and other related illnesses may be better controlled. May nutritionists also take note, as it is very apparent that what people are eating may not be good for them for, as Lucretius wrote in 55 B.C. in his treatise, “De Rerum Natura,” “One man's meat is another man's poison.”