Excretion of Urinary Mucoprotein Following Parathyroid Extract in Rats.
- 1 November 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 84 (2) , 336-338
- https://doi.org/10.3181/00379727-84-20639
Abstract
Control rats excrete, over a 72-hr. period, 0.35-1.92 (mean: 1.08) mg. urinary mucoprotein detd. as mannose-galactose standard. Following the injn. of 1000 units of parathyroid extract (Lilly), the excretion of mucoprotein increased significantly to 0.52-4.52 (mean 2.84) mg. This in-crease is correlated in time with the dissolution of bone matrix, with an increase in serum mucoprotein, and with the appearance of mucoprotein granules in kidney tubule cells and mucoprotein-containing casts in tubules.Keywords
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