Significance of Mitochondria for Porphyrin and Heme Biosynthesis
- 30 January 1959
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 129 (3344) , 275-276
- https://doi.org/10.1126/science.129.3344.275
Abstract
It is concluded that mitochondria are involved in three steps of porphyrin and heme biosynthesis—first, in the formation of δ-aminolevulinic acid from glycine and active succinate; second, in the synthesis of protoporphyrin; third, in the incorporation of iron into the porphyrin ring—that is, in heme formation.Keywords
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