Proinflammatory cytokines and hemostatic system in patients with chronic obstructive pulmonary disease
- 1 January 1997
- journal article
- research article
- Published by Taylor & Francis in Platelets
- Vol. 8 (4) , 255-260
- https://doi.org/10.1080/09537109777294
Abstract
The prothrombotic state frequently observed in patients with chronic obstructive pulmonary disease (COPD) may be related to a systemic inflammatory response. In the present study plasma interleukin-6 (IL-6), IL-2 and IL-1 levels have been investigated in 33 patients with COPD. In vitro platelet activity, plasma C-reactive protein (CRP) and fibrinogen levels were also determined in all patients. The results obtained demonstrated that plasma IL-6 levels were significantly higher in the patient group compared with a control population ageand sex-matched ( PKeywords
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