Synthesis and biological actions of optically active enediynes related to dynemicin A
- 1 January 1992
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 21,p. 1542-1544
- https://doi.org/10.1039/c39920001542
Abstract
Enantiomerically pure enediynes (+)-2 and (–)-2 were synthesized using a chiral resolution method and were shown to exhibit different cytotoxicities against a number of tumour cells.Keywords
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