Effect of Pyridoxine on Tryptophan Metabolism in Rheumatoid Arthritis
Open Access
- 1 December 1962
- journal article
- research article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 21 (4) , 388-391
- https://doi.org/10.1136/ard.21.4.388
Abstract
Kynurenine output after L-tryptophan increased in the majority of patients with rheumatoid arthritis. This abnormality was unrelated to the duration, activity, or severity of the disease. In a majority of the patients administration of large doses of pyridoxine orally and/or intramuscularly produced a reduction in kynurenine output after tryptophan.Keywords
This publication has 7 references indexed in Scilit:
- Metabolism of Tryptophan in Rheumatoid ArthritisAnnals of the Rheumatic Diseases, 1962
- The determination in urine of some metabolites of tryptophan-kynurenine, anthranilic acid and 3-hydroxyanthranilic acid-and reference to the presence of o-aminophenol in urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1959
- Genetic Studies on Rheumatoid ArthritisAnnals of the Rheumatic Diseases, 1958
- Course and Prognosis in Rheumatoid ArthritisAnnals of the Rheumatic Diseases, 1957
- Scleroderma (Acrosclerosis)Journal of Investigative Dermatology, 1957
- KYNURENINASE FROM NEUROSPORA: PURIFICATION AND PROPERTIESJournal of Biological Chemistry, 1953