Effects of desglycinamide-arginine-vasopressin (DG-AVP) on memory processes in diabetes insipidus patients and non-diabetic subjects
- 1 February 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 102 (2) , 205-212
- https://doi.org/10.1530/acta.0.1020205
Abstract
The effects of desglycinamide9-arginine8-vasopressin (DG-AVP) on memory processes were studied in patients with central diabetes insipidus (DI) and in non-diabetic control patients. Acute i.m. injection of DG-AVP improved some aspects of short-term memory. Subchronic intranasal administration of DG-AVP facilitated short-term memory more consistently and in addition improved long-term memory. DG-AVP increased the attention, but only in the non-diabetic subjects. The effects of DG-AVP on memory processes persisted after discontinuation of treatment. DG-AVP did not affect the parameters for water and electrolyte metabolism, blood pressure and pulse rate neither in DI nor in the control patients. The memory effects of DG-AVP are probably mediated by a direct action on the CNS.This publication has 1 reference indexed in Scilit:
- Effects of Vasopressin on Human Memory FunctionsScience, 1981