Increased Frequency of HL‐A8 in Sjogren's Syndrome
- 1 October 1975
- journal article
- Published by Wiley in Tissue Antigens
- Vol. 6 (4) , 342-346
- https://doi.org/10.1111/j.1399-0039.1975.tb00653.x
Abstract
The histocompatibility antigen, HL‐A8, was found to be elevated in patients with Sjogren's syndrome. Among 24 patients, the frequency of HL‐A8 was 58% compared to 21% among controls (P < 0.001 after correction). With the addition of this disorder to the list of other autoimmune diseases associated with HL‐A8, it now seems possible to postulate a single basis autoimmune defect gene in high linkage disequilibrium with HL‐A8.Keywords
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