A field isolate of Sendai virus: its high virulence to mice and genetic divergence from prototype strains
- 1 March 1994
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 135 (1-2) , 159-164
- https://doi.org/10.1007/bf01309773
Abstract
A field isolate of Sendai virus, the Hamamatsu strain, was far more virulent in mice than the prototype Z strain. The Hamamatsu strain replicated more efficiently in the mouse lung than the Z strain, causing deteriorating lung lesions. Nucleotide sequence analysis of the HN, F and M genes revealed that the Hamamatsu strain was divergent from the prototype Z, Harris and Fushimi strains.Keywords
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