Uric Acid and Chronic Musculoskeletal Complaints

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Abstract
The relation between chronic musculoskeletal complaints and serum uric acid was examined in 737 men and 771 women (40–42 years old). The study is cross - sectional and part of the National Health Screening Service county studies in Norway. Both men and women with chronic musculoskeletal complaints had significantly higher s-urate means than persons without such complaints. Moreover, the prevalence of chronic musculoskeletal complaints (gout excluded) changed significantly across increasing s-urate levels also within the normal distribution of s-urate. Multivariate logistic regression analysis showed that the s-urate odds ratio for chronic complaints rose in a linear manner across these s-urate levels (adjusted for 12 other independent variables that may interfere with uric acid). Such a relation has not to our knowledge been previously described.
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