Prothracarcin, a novel antitumor antibiotic.
- 1 January 1982
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 35 (8) , 972-978
- https://doi.org/10.7164/antibiotics.35.972
Abstract
A novel antibiotic, prothracarcin, was isolated from the culture broth of Streptomyces umbrosus ssp. raffinophilus DO-62. The antibiotic has the molecular formula of C14H14N2O and belongs to the pyrrolo [1,4]benzodiazepine antibiotics. Its structure was elucidated by mass and NMR spectra. It is active against gram-positive and negative bacteria as well as experimental murine tumor sarcoma 180 and leukemia P388.This publication has 1 reference indexed in Scilit:
- Tetrocarcins, novel antitumor antibiotics. II. Isolation, characterization and antitumor activity.The Journal of Antibiotics, 1980