Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors
- 1 December 1998
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 8 (24) , 3631-3636
- https://doi.org/10.1016/s0960-894x(98)00669-6
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- On the size of the active site in proteases. I. PapainPublished by Elsevier ,2005
- HIV-Protease InhibitorsNew England Journal of Medicine, 1998
- Clinically effective HIV-1 protease inhibitorsDrug Discovery Today, 1997
- Recent developments in HIV protease inhibitor researchExpert Opinion on Therapeutic Patents, 1997
- Kinetic Characterization of Human Immunodeficiency Virus Type-1 Protease-resistant VariantsJournal of Biological Chemistry, 1996
- 141W94Drugs of the Future, 1996
- Nonpeptidal P2 Ligands for HIV Protease Inhibitors: Structure-Based Design, Synthesis, and Biological EvaluationJournal of Medicinal Chemistry, 1996
- Expedient Method for the Solid-Phase Synthesis of Aspartic Acid Protease Inhibitors Directed toward the Generation of LibrariesJournal of Medicinal Chemistry, 1995
- Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzymeJournal of the American Chemical Society, 1995
- Benzocycloalkyl amines as novel C-termini for HIV protease inhibitorsJournal of Medicinal Chemistry, 1991