Tumor Necrosis Factor (TNF)-α Inhibits Insulin Signaling through Stimulation of the p55 TNF Receptor and Activation of Sphingomyelinase
Open Access
- 1 May 1996
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 271 (22) , 13018-13022
- https://doi.org/10.1074/jbc.271.22.13018
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Two tumour necrosis factor receptors: structure and functionPublished by Elsevier ,2000
- Phosphorylation of Raf by ceramide-activated protein kinaseNature, 1995
- Tumor Necrosis Factor α-induced Phosphorylation of Insulin Receptor Substrate-1 (IRS-1)Journal of Biological Chemistry, 1995
- 4PS/Insulin Receptor Substrate (IRS)-2 Is the Alternative Substrate of the Insulin Receptor in IRS-1-deficient MicePublished by Elsevier ,1995
- Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.Journal of Clinical Investigation, 1995
- The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.Journal of Clinical Investigation, 1995
- RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell deathCell, 1995
- Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.Journal of Clinical Investigation, 1994
- A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorCell, 1994
- Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceScience, 1993